BN104 — Investigational Agent

Menin Inhibitor · Phase 1/2 · Biolino Bioscience / BioNova

Mechanism of Action

Small-molecule inhibitor of the menin-KMT2A (MLL) protein-protein interaction, disrupting the transcriptional complex that maintains leukemogenic HOX/MEIS1 programs in KMT2A-rearranged and NPM1-mutated acute leukemias.

Investigational Indications

Key Trials