LY4101174 — Investigational Agent
Antibody-Drug Conjugate · Phase 1 · Eli Lilly
Mechanism of Action
A Nectin-4-directed antibody-drug conjugate that binds Nectin-4 overexpressed on urothelial and other epithelial tumors and delivers a cytotoxic payload intracellularly after internalization.
Investigational Indications
- Advanced/metastatic urothelial carcinoma
- Nectin-4-expressing solid tumors