MRG002 — Investigational Agent

Antibody-Drug Conjugate · Phase 2 · Shanghai Miracogen

Mechanism of Action

MRG002 is a HER2-directed antibody-drug conjugate linking an anti-HER2 monoclonal antibody to a monomethyl auristatin E (MMAE) microtubule-inhibitor payload via a cleavable linker. It delivers cytotoxic payload to HER2-expressing cells, including HER2-low tumors.

Investigational Indications

Key Trials