RC148 — Investigational Agent

Bispecific Antibody · Phase 1 · RemeGen

Mechanism of Action

RC148 is a PD-1 x VEGF bispecific antibody that simultaneously blocks PD-1 checkpoint signaling and sequesters VEGF, combining immune reactivation with anti-angiogenesis in a single molecule. It is studied as monotherapy and in ADC combinations for GI and other solid tumors.

Investigational Indications

Key Trials