Enterestrant — Investigational Agent
Selective Estrogen Receptor Degrader · Phase 1/2 · Zenopharm
Mechanism of Action
ZB716 (enterestrant) is an orally bioavailable selective estrogen receptor degrader that binds and promotes proteasomal degradation of ERalpha, providing fulvestrant-like activity without intramuscular injection.
Investigational Indications
- ER-positive/HER2-negative locally advanced or metastatic breast cancer