CD19 — Targeted Therapies, Trials & Pipeline
A pan-B-cell antigen targeted by CAR-T cells, bispecifics and ADCs in B-cell malignancies.
Approved drugs targeting CD19
axicabtagene ciloleucel
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blinatumomab
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brexucabtagene autoleucel
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lisocabtagene maraleucel
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loncastuximab tesirine-lpyl
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Obecabtagene autoleucel
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Tafasitamab
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Tisagenlecleucel
Investigational pipeline agents
Azercabtagene zapreleucel
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CTX112
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GC012F
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GNC-038
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NKX019
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Obecabtagene autoleucel
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Surovatamig
Landmark trials
TRANSFORM
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ZUMA-1